Somatropin (Humatrope) 72 IU
To minimize the rate of side-effects, a retrospective analysis of 28 studies of GH replacement therapy in adults indicates that the maintenance dose should usually not exceed 1.0 IU/m2/day (about 1.5-2.0 IU/day) in GHD patients 40-60 years old, or 1.5 IU/m2/day (about 2.5-3.0 IU/day) in GHD patients 20-40 years old. 1 mg of somatropin corresponds to 3 IU of somatropin. Norditropin NordiFlex is available in three strengths: 5 mg/1.5 ml, 10 mg/1.5 ml and 15 mg/1.5 ml (equivalent to 3.3 mg/ml, 6.7 mg/ml and 10 mg/ml, respectively). Each HUMATROPE cartridge contains 6 mg (18 IU), 12 mg (36 IU) or 24 mg (72 IU) of human growth hormone and when reconstituted with the diluent provided the cartridge contains 2.07 mg/mL, 4.17 mg/mL or 8.46 mg/mL somatropin respectively The cartridge also contains the inactive ingredients mannitol, glycine and dibasic. In all subjects taking a daily dose of 2+iu (4+ days per week) we measured significant bodyfat losses over the first 3-4 weeks of administration. Subjects using less than 2iu per day failed to show any response.
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